Co-occurring physical health challenges in neurodivergent children and young people: A topical review and recommendation

Added on 04/11/2024

Type de contenu

Journal article of the type Perspective ( ; english)

Co-occurring physical health challenges in neurodivergent children and young people: A topical review and recommendation published in the journal "Child care in practice" n°29, vol.1, 19 pages , doi: 10.1080/13575279.2022.2149471

*Two co-authors had publicly identified as autistic. [Learn more about this mention]

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Summary/Presentation

Neurodivergence has been established as associated with a significant number of co-occurring physical conditions, particularly for autistic individuals who are at risk for increased pain, hypermobility (including Ehlers-Danlos Syndrome) and gastrointestinal problems. However, data, so far, has been focused on adults and generally limited to discussions of condition prevalence alone. The following article will present a topical review of the literature considering evidence for increased physical health concerns within neurodivergent populations, particularly autistic individuals, with a focus on the impact that these physical health concerns may have in an educational setting. The impact of physical health concerns within neurodivergent populations in an educational setting may be concerning. Such populations may face a range of challenges in obtaining appropriate support for physical conditions. We discuss a number of said challenges including; communication challenges, misattributing physical health symptoms as a part of neurodivergence, and a history of not being believed, which limits symptomatic reporting. We further consider the potential impact these physical health concerns may have on scholastic and social development, such as impacts for attainment and attendance. Furthermore, we provide recommendations for teachers, parents/carers and other allied professionals in young people’s lives, on supporting young neurodivergent people with physical health concerns.


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(1) References in blue are resources listed on our site.

(2) Authors listed in this bibliography whose names are in color have published other resources referenced on the site. Clicking on the name allows you to see the list of resources they have published and shared on the site.

(3) Authors whose names are followed by an asterisk have publicly disclosed being autistic.


  • Census Gov. (2022). "Educational attainment". (Source)

  • Department for Education. (2013). "Ensuring a good education for children who cannot attend school because of health needs: Statutory guidance for local authorities". (Source)

  • Department for Education. (2022a). "The link between absence and attainment at KS2 and KS4". (Source)

  • Department for Education. (2022b). "School attendance: Guidance for maintained schools, academies, independent schools and local authorities". (Source)

  • Jan. Green* (2020). "Raising awareness of pupils with Ehlers-Danlos syndromes / Hypermobility spectrum disorders". edpsy.org.uk. (Source)

  • Hutchinson, J. & Crenna-Jenning, W. (2019). "Unexplained pupil exits from schools: A growing problem?". (Source)

  • National Autistic Society. (2019). "Reasonable adjustments for autistic pupils' sensory differences". (Source)

  • National Autistic Society. (2020). "Autistic fatigue and burnout". (Source)

  • National Institute for Health and Care Excellence (NICE). (2020). "NICEimpact children and young people's healthcare". (Source)

  • Public Health England. (2014). "The link between pupil health and wellbeing and attainment". (Source)

  • The School Toolkit for EDS and JHS. (2021a). "About the toolkit". (Source)

  • The School Toolkit for EDS and JHS. (2021b). "Reasonable adjustments in school". (Source)

  • The School Toolkit for EDS and JHS. (2021c). "The school toolkit". (Source)

  • The School Toolkit for EDS and JHS. (2021d). "What are hypermobility, JHS and EDS?". (Source)

  • S. Stanford (n.d.). "Dehumanization, dismissal, and disparities: An analysis of harmful trends in Healthcare providers' interactions with Autistic Patients". (Source)

  • N. Adib, K. Davies, R. Grahame, P. Woo, K. Murray (2005). "Joint hypermobility syndrome in childhood. A not so benign multisystem disorder?". Rheumatology, 44(6). doi:10.1093/rheumatology/keh557

  • M. Allison, E. Attisha, I., M. Lerner, C. Duncan De Pinto, N. Savio Beers, E. Gibson, P. Gorski, C. Kjolhede, S. O’Leary, H. Schumacher, A. Weiss-Harrison (2019). "The Link Between School Attendance and Good Health". Pediatrics, 143(2). doi:10.1542/peds.2018-3648

  • K. Atwell, W. Michael, J. Dubey, S. James, A. Martonffy, S. Anderson, N. Rudin, S. Schrager (2021). "Diagnosis and Management of Hypermobility Spectrum Disorders in Primary Care". J Am Board FamMed, 34(4). doi:10.3122/jabfm.2021.04.200374

  • C. Baeza-Velasco, D. Cohen, C. Hamonet, E. Vlamynck, L. Diaz, C. Cravero, E. Cappe, V. Guinchat (2018). "Autism, Joint Hypermobility-Related Disorders and Pain". Front. Psychiatry, 9. doi:10.3389/fpsyt.2018.00656

  • C. Baeza-Velasco, L. Sinibaldi, M. Castori (2018). "Attention-deficit/hyperactivity disorder, joint hypermobility-related disorders and pain: expanding body-mind connections to the developmental age". ADHD Atten Def Hyp Disord, 10(3). doi:10.1007/s12402-018-0252-2

  • N. Bayer, H. Wang, J. Yu, D. Kuo, J. Halterman, Y. Li (2021). "A National Mental Health Profile of Parents of Children With Medical Complexity". Pediatrics, 148(2). doi:10.1542/peds.2020-023358

  • P. Beighton, L. Solomon, C. Soskolne (1973). "Articular mobility in an African population.". Annals of the Rheumatic Diseases, 32(5). doi:10.1136/ard.32.5.413

  • C. Black, D. Drossman, N. Talley, J. Ruddy, A. Ford (2020). "Functional gastrointestinal disorders: advances in understanding and management". The Lancet, 396(10263). doi:10.1016/s0140-6736(20)32115-2

  • T. Buck, J. Viskochil, M. Farley, H. Coon, W. McMahon, J. Morgan, D. Bilder (2014). "Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder". J Autism Dev Disord, 44(12). doi:10.1007/s10803-014-2170-2

  • L. Calder, V. Hill, E. Pellicano (2013). "'Sometimes I want to play by myself': Understanding what friendship means to children with autism in mainstream primary schools". Autism, 17(3). doi:10.1177/1362361312467866

  • R. Casale, F. Atzeni, L. Bazzichi, G. Beretta, E. Costantini, P. Sacerdote, C. Tassorelli (2021). "Pain in Women: A Perspective Review on a Relevant Clinical Issue that Deserves Prioritization". Pain Ther, 10(1). doi:10.1007/s40122-021-00244-1

  • M. Castori (2012). "Ehlers-Danlos Syndrome, Hypermobility Type: An Underdiagnosed Hereditary Connective Tissue Disorder with Mucocutaneous, Articular, and Systemic Manifestations". ISRN Dermatology, 2012. doi:10.5402/2012/751768

  • M. Cattalini, R. Khubchandani, R. Cimaz (2015). "When flexibility is not necessarily a virtue: a review of hypermobility syndromes and chronic or recurrent musculoskeletal pain in children". Pediatr Rheumatol, 13(1). doi:10.1186/s12969-015-0039-3

  • M. Cederlöf, H. Larsson, P. Lichtenstein, C. Almqvist, E. Serlachius, J. Ludvigsson (2016). "Nationwide population-based cohort study of psychiatric disorders in individuals with Ehlers–Danlos syndrome or hypermobility syndrome and their siblings". BMC Psychiatry, 16(1). doi:10.1186/s12888-016-0922-6

  • P. Chakraborty, K. Carpenter, S. Major, M. Deaver, S. Vermeer, B. Herold, L. Franz, J. Howard, G. Dawson (2021). "Gastrointestinal problems are associated with increased repetitive behaviors but not social communication difficulties in young children with autism spectrum disorders". Autism, 25(2). doi:10.1177/1362361320959503

  • L. Clouder, M. Karakus, A. Cinotti, M. Virginia Ferreyra, G. Amador Fierros, P. Rojo (2020). "Neurodiversity in higher education: a narrative synthesis". High Educ, 80(4). doi:10.1007/s10734-020-00513-6

  • N. Crossley, D. Hewitt (2021). "Inclusion: A Principled Guide for School Leaders". Routledge

  • J. Csecs, V. Iodice, C. Rae, A. Brooke, R. Simmons, L. Quadt, G. Savage, N. Dowell, F. Prowse, K. Themelis, C. Mathias, H. Critchley, J. Eccles (2022). "Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain". Front. Psychiatry, 12. doi:10.3389/fpsyt.2021.786916

  • J. Csecs, V. lodice, C. Rae, A. Brooke, R. Simmons, N. Dowell, F. Prowse, K. Themelis, H. Critchley, J. Eccles (2020). "Increased rate of joint hypermobility in autism and related neurodevelopmental conditions is linked to dysautonomia and pain". medRxiv. doi:10.1101/2020.09.14.20194118

  • A. Dahan, M. van Velzen, M. Niesters (2014). "Comorbidities and the Complexities of Chronic Pain". Anesthesiology, 121(4). doi:10.1097/aln.0000000000000402

  • J. Demmler, M. Atkinson, E. Reinhold, E. Choy, R. Lyons, S. Brophy (2019). "Diagnosed prevalence of Ehlers-Danlos syndrome and hypermobility spectrum disorder in Wales, UK: a national electronic cohort study and case–control comparison". BMJ Open, 9(11). doi:10.1136/bmjopen-2019-031365

  • J. DiFrancisco-Donoghue, V. Southard, M. Margulies, M. Jung, A. Allera, B. Riley (2022). "Assessment of gastrointestinal function and its' effect on bone mineral density and body composition in hypermobility spectrum disorder and hypermobile Ehlers-Danlos syndrome". Journal of Clinical Densitometry, 25(4). doi:10.1016/j.jocd.2022.07.005

  • A. Jayne Doherty, H. Atherton, P. Boland, R. Hastings, L. Hives, K. Hood, L. James-Jenkinson, R. Leavey, E. Randell, J. Reed, L. Taggart, N. Wilson, U. Chauhan (2020). "Barriers and facilitators to primary health care for people with intellectual disabilities and/or autism: an integrative review". BJGP Open, 4(3). doi:10.3399/bjgpopen20x101030

  • O. Doody, M. Bailey (2019). "Understanding pain physiology and its application to person with intellectual disability". J Intellect Disabil, 23(1). doi:10.1177/1744629517708680

  • D. DuBois, S. Ameis, M. Lai, M. Casanova, P. Desarkar (2016). "Interoception in Autism Spectrum Disorder: A review". Intl J of Devlp Neuroscience, 52(1). doi:10.1016/j.ijdevneu.2016.05.001

  • J. Eccles, F. Beacher, M. Gray, C. Jones, L. Minati, N. Harrison, H. Critchley (2012). "Brain structure and joint hypermobility: Relevance to theexpression of psychiatric symptoms". Br JPsychiatry, 200(6). doi:10.1192/bjp.bp.111.092460

  • J. Eccles, V. Iodice, N. Dowell, A. Owens, L. Hughes, S. Skipper, Y. Lycette, K. Humphries, N. Harrison, C. Mathias, H. Critchley (2014). "JOINT HYPERMOBILITY AND AUTONOMIC HYPERACTIVITY: RELEVANCE TO NEURODEVELOPMENTAL DISORDERS". Journal of Neurology, Neurosurgery & Psychiatry, 85(8). doi:10.1136/jnnp-2014-308883.9

  • R. H.H. Engelbert, B. Juul‐Kristensen, V. Pacey, I. de Wandele, S. Smeenk, N. Woinarosky, S. Sabo, M. Scheper, L. Russek, J. Simmonds (2017). "The evidence‐based rationale for physical therapy treatment of children, adolescents, and adults diagnosed with joint hypermobility syndrome/hypermobile Ehlers Danlos syndrome". American J of Med Genetics Pt C, 175(1). doi:10.1002/ajmg.c.31545

  • S. Friedrichsdorf, J. Giordano, K. Desai Dakoji, A. Warmuth, C. Daughtry, C. Schulz (2016). "Chronic Pain in Children and Adolescents: Diagnosis and Treatment of Primary Pain Disorders in Head, Abdomen, Muscles and Joints". Children, 3(4). doi:10.3390/children3040042

  • S. Garfinkel, C. Tiley, S. O'Keeffe, N. Harrison, A. Seth, H. Critchley (2016). "Discrepancies between dimensions of interoception in autism: Implications for emotion and anxiety". Biological Psychology, 114. doi:10.1016/j.biopsycho.2015.12.003

  • Y. Gazit, G. Jacob, R. Grahame (2016). "Ehlers–Danlos Syndrome—Hypermobility Type: A Much Neglected Multisystemic Disorder". Rambam Maimonides Med J, 7(4). doi:10.5041/rmmj.10261

  • C. Gensemer, R. Burks, S. Kautz, D. Judge, M. Lavallee, R. Norris (2021). "Hypermobile Ehlers‐Danlos syndromes: Complex phenotypes, challenging diagnoses, and poorly understood causes". Developmental Dynamics, 250(3). doi:10.1002/dvdy.220

  • G. Ghibellini, F. Brancati, M. Castori (2015). "Neurodevelopmental attributes of joint hypermobility syndrome/Ehlers–Danlos syndrome, hypermobility type: Update and perspectives". American J of Med Genetics Pt C, 169(1). doi:10.1002/ajmg.c.31424

  • T. Hadjistavropoulos, K. Craig, S. Duck, A. Cano, L. Goubert, P. Jackson, J. Mogil, P. Rainville, M. Sullivan, A. de Williams, T. Vervoort, T. Dever Fitzgerald (2011). "A biopsychosocial formulation of pain communication.". Psychological Bulletin, 137(6). doi:10.1037/a0023876

  • B. Hamre, A. Partee, C. Mulcahy (2017). "Enhancing the Impact of Professional Development in the Context of Preschool Expansion". AERA Open, 3(4). doi:10.1177/2332858417733686

  • F. Happé, H. Mansour, P. Barrett, T. Brown, P. Abbott, R. Charlton (2016). "Demographic and Cognitive Profile of Individuals Seeking a Diagnosis of Autism Spectrum Disorder in Adulthood". J Autism Dev Disord, 46(11). doi:10.1007/s10803-016-2886-2

  • D. Higgins, A. Martin, D. Baker, J. Vasterling, V. Risbrough (2018). "The Relationship Between Chronic Pain and Neurocognitive Function". The Clinical Journal of Pain, 34(3). doi:10.1097/ajp.0000000000000536

  • C. Holingue, O. Poku, D. Pfeiffer, S. Murray, M. Daniele Fallin (2022). "Gastrointestinal concerns in children with autism spectrum disorder: A qualitative study of family experiences". Autism, 26(7). doi:10.1177/13623613211062667

  • S. Ibrahim, R. Voigt, S. Katusic, A. Weaver, W. Barbaresi (2009). "Incidence of Gastrointestinal Symptoms in Children With Autism: A Population-Based Study". Pediatrics, 124(2). doi:10.1542/peds.2008-2933

  • F. Idris, Z. Hassan, A. Ya’acob, S. Kaur Gill, N. Aziah Mohd Awal (2012). "The Role of Education in Shaping Youth's National Identity". Procedia - Social and Behavioral Sciences, 59. doi:10.1016/j.sbspro.2012.09.299

  • M. Jackson (2013). "The special educational needs of adolescents living with chronic illness: a literature review". International Journal of Inclusive Education, 17(6). doi:10.1080/13603116.2012.676085

  • S. Jackson, L. Hart, J. Thierfeld Brown, F. Volkmar (2018). "Brief Report: Self-Reported Academic, Social, and Mental Health Experiences of Post-Secondary Students with Autism Spectrum Disorder". J Autism Dev Disord, 48(3). doi:10.1007/s10803-017-3315-x

  • A. John, Y. Friedmann, M. DelPozo-Banos, A. Frizzati, T. Ford, A. Thapar (2022). "Association of school absence and exclusion with recorded neurodevelopmental disorders, mental disorders, or self-harm: a nationwide, retrospective, electronic cohort study of children and young people in Wales, UK". The Lancet Psychiatry, 9(1). doi:10.1016/s2215-0366(21)00367-9

  • C. Kasari, J. Locke, A. Gulsrud, E. Rotheram-Fuller (2011). "Social Networks and Friendships at School: Comparing Children With and Without ASD". J Autism Dev Disord, 41(5). doi:10.1007/s10803-010-1076-x

  • V. Kentrou, D. MJ de Veld, K. JK Mataw, S. Begeer (2019). "Delayed autism spectrum disorder recognition in children and adolescents previously diagnosed with attention-deficit/hyperactivity disorder". Autism, 23(4). doi:10.1177/1362361318785171

  • E. Kindgren, A. Quiñones Perez, R. Knez (2021). "Prevalence of ADHD and Autism Spectrum Disorder in Children with Hypermobility Spectrum Disorders or Hypermobile Ehlers-Danlos Syndrome: A Retrospective Study". NDT, Volume 17. doi:10.2147/ndt.s290494

  • A. Kirby, R. Davies (2007). "Developmental Coordination Disorder and Joint Hypermobility Syndrome – overlapping disorders? Implications for research and clinical practice". Child, 33(5). doi:10.1111/j.1365-2214.2006.00694.x

  • M. Kofler, D. Sarver, S. Harmon, A. Moltisanti, P. Aduen, E. Soto, N. Ferretti (2018). "Working memory and organizational skills problems in ADHD". Child Psychology Psychiatry, 59(1). doi:10.1111/jcpp.12773

  • S. Kosola, L. Mundy, S. Sawyer, L. Canterford, D. van der Windt, K. Dunn, G. Patton (2017). "Pain and learning in primary school: a population-based study". Pain, 158(9). doi:10.1097/j.pain.0000000000000984

  • K. Kovacic, T. Chelimsky, M. Sood, P. Simpson, M. Nugent, G. Chelimsky (2014). "Joint Hypermobility: A Common Association with Complex Functional Gastrointestinal Disorders". The Journal of Pediatrics, 165(5). doi:10.1016/j.jpeds.2014.07.021

  • B. Kumar, P. Lenert (2017). "Joint Hypermobility Syndrome: Recognizing a Commonly Overlooked Cause of Chronic Pain". The American Journal of Medicine, 130(6). doi:10.1016/j.amjmed.2017.02.013

  • C. Kwan, M. Gitimoghaddam, J. Collet (2020). "Effects of Social Isolation and Loneliness in Children with Neurodevelopmental Disabilities: A Scoping Review". Brain Sciences, 10(11). doi:10.3390/brainsci10110786

  • J. Langhinrichsen-Rohling, C. Lewis, S. McCabe, E. Lathan, G. Agnew, C. Selwyn, M. Gigler (2021). "They've been BITTEN: reports of institutional and provider betrayal and links with Ehlers-Danlos Syndrome patients' current symptoms, unmet needs and healthcare expectations". Therapeutic Advances in Rare Disease, 2. doi:10.1177/26330040211022033

  • C. Wiwe Lipsker, S. Bölte, T. Hirvikoski, M. Lekander, L. Holmström, R. Wicksell (2018). "Prevalence of autism traits and attention-deficit hyperactivity disorder symptoms in a clinical sample of children and adolescents with chronic pain". JPR, Volume 11. doi:10.2147/jpr.s177534

  • F. Malfait, C. Francomano, P. Byers, J. Belmont, B. Berglund, J. Black, L. Bloom, J. Bowen, A. Brady, N. Burrows, M. Castori, H. Cohen, M. Colombi, S. Demirdas, J. De Backer, A. De Paepe, S. Fournel‐Gigleux, M. Frank, N. Ghali, C. Giunta, R. Grahame, A. Hakim, X. Jeunemaitre, D. Johnson, B. Juul‐Kristensen, I. Kapferer‐Seebacher, H. Kazkaz, T. Kosho, M. Lavallee, H. Levy, R. Mendoza‐Londono, M. Pepin, F. Michael Pope, E. Reinstein, L. Robert, M. Rohrbach, L. Sanders, G. Sobey, T. Van Damme, A. Vandersteen, C. van Mourik, N. Voermans, N. Wheeldon, J. Zschocke, B. Tinkle (2017). "The 2017 international classification of the Ehlers–Danlos syndromes". American J of Med Genetics Pt C, 175(1). doi:10.1002/ajmg.c.31552

  • A. Mannion, G. Leader (2014). "Gastrointestinal Symptoms in Autism Spectrum Disorder: A Literature Review". Rev J Autism Dev Disord, 1(1). doi:10.1007/s40489-013-0007-0

  • F. May, T. Ford, A. Janssens, T. Newlove‐Delgado, A. Emma Russell, J. Salim, O. Ukoumunne, R. Hayes (2021). "Attainment, attendance, and school difficulties in UK primary schoolchildren with probable ADHD". Brit J of Edu Psychol, 91(1). doi:10.1111/bjep.12375

  • C. McKeown, E. Hisle-Gorman, M. Eide, G. Gorman, C. Nylund (2013). "Association of Constipation and Fecal Incontinence With Attention-Deficit/Hyperactivity Disorder". Pediatrics, 132(5). doi:10.1542/peds.2013-1580

  • J. McLeod, E. Meanwell, A. Hawbaker (2019). "The Experiences of College Students on the Autism Spectrum: A Comparison to Their Neurotypical Peers". J Autism Dev Disord, 49(6). doi:10.1007/s10803-019-03910-8

  • J. Morley, J. Morris, M. Berg-Weger, S. Borson, B. Carpenter, N. del Campo, B. Dubois, K. Fargo, L. Jaime Fitten, J. Flaherty, M. Ganguli, G. Grossberg, T. Malmstrom, R. Petersen, C. Rodriguez, A. Saykin, P. Scheltens, E. Tangalos, J. Verghese, G. Wilcock, B. Winblad, J. Woo, B. Vellas (2015). "Brain Health: The Importance of Recognizing Cognitive Impairment: An IAGG Consensus Conference". Journal of the American Medical Directors Association, 16(9). doi:10.1016/j.jamda.2015.06.017

  • K. Murray (2006). "Hypermobility disorders in children and adolescents". Best Practice & Research Clinical Rheumatology, 20(2). doi:10.1016/j.berh.2005.12.003

  • L. Newman‐Ford, K. Fitzgibbon, S. Lloyd, S. Thomas (2008). "A large‐scale investigation into the relationship between attendance and attainment: a study using an innovative, electronic attendance monitoring system". Studies in Higher Education, 33(6). doi:10.1080/03075070802457066

  • B. Newton, J. Southall, J. Raphael, R. Ashford, K. LeMarchand (2013). "A Narrative Review of the Impact of Disbelief in Chronic Pain". Pain Management Nursing, 14(3). doi:10.1016/j.pmn.2010.09.001

  • T. Palermo, C. Eccleston (2009). "Parents of children and adolescents with chronic pain". Pain, 146(1). doi:10.1016/j.pain.2009.05.009

  • E. Palser, C. Palmer, A. Galvez-Pol, R. Hannah, A. Fotopoulou, J. Kilner (2018). "Alexithymia mediates the relationship between interoceptive sensibility and anxiety". PLoS ONE, 13(9). doi:10.1371/journal.pone.0203212

  • G. Pepe, B. Giusti, E. Sticchi, R. Abbate, G. Gensini, S. Nistri (2016). "Marfan syndrome: current perspectives". TACG. doi:10.2147/tacg.s96233

  • A. Piller, B. Pfeiffer (2016). "The Sensory Environment and Participation of Preschool Children With Autism Spectrum Disorder". OTJR: Occupational Therapy Journal of Research, 36(3). doi:10.1177/1539449216665116

  • K. Price, U. Butler (2001). "Bowel and bladder management in children with disabilities". Current Paediatrics, 11(2). doi:10.1054/cupe.2000.0158

  • L. Quadt, S. Garfinkel, J. Mulcahy, D. EO Larsson, M. Silva, A. Jones, C. Strauss, H. Critchley (2021). "Interoceptive training to target anxiety in autistic adults (ADIE): A single-center, superiority randomized controlled trial". EClinicalMedicine, 39. doi:10.1016/j.eclinm.2021.101042

  • S. Raja, D. Carr, M. Cohen, N. Finnerup, H. Flor, S. Gibson, F. Keefe, J. Mogil, M. Ringkamp, K. Sluka, X. Song, B. Stevens, M. Sullivan, P. Tutelman, T. Ushida, K. Vader (2020). "The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises". Pain, 161(9). doi:10.1097/j.pain.0000000000001939

  • C. Rattaz, A. Dubois, C. Michelon, M. Viellard, F. Poinso, A. Baghdadli (2013). "How do children with autism spectrum disorders express pain? A comparison with developmentally delayed and typically developing children". Pain, 154(10). doi:10.1016/j.pain.2013.06.011

  • B. Rodriguez, A. Hochstrasser, P. Eugster, E. Grouzmann, R. Müri, W. Z’Graggen (2022). "Brain fog in neuropathic postural tachycardia syndrome may be associated with autonomic hyperarousal and improves after water drinking". Front. Neurosci., 16. doi:10.3389/fnins.2022.968725

  • J. Ross, R. Grahame (2011). "Joint hypermobility syndrome". BMJ, 342(jan20 1). doi:10.1136/bmj.c7167

  • R. Ruscheweyh, F. Nees, M. Marziniak, S. Evers, H. Flor, S. Knecht (2011). "Pain Catastrophizing and Pain-related Emotions". The Clinical Journal of Pain, 27(7). doi:10.1097/ajp.0b013e31820fde1b

  • M. Rutherford, K. McKenzie, T. Johnson, C. Catchpole, A. O’Hare, I. McClure, K. Forsyth, D. McCartney, A. Murray (2016). "Gender ratio in a clinical population sample, age of diagnosis and duration of assessment in children and adults with autism spectrum disorder". Autism, 20(5). doi:10.1177/1362361315617879

  • R. Sala, L. Amet, N. Blagojevic-Stokic, P. Shattock, P. Whiteley (2020). "<p>Bridging the Gap Between Physical Health and Autism Spectrum Disorder</p>". NDT, Volume 16. doi:10.2147/ndt.s251394

  • Y. Saqr, E. Braun, K. Porter, D. Barnette, C. Hanks (2018). "Addressing medical needs of adolescents and adults with autism spectrum disorders in a primary care setting". Autism, 22(1). doi:10.1177/1362361317709970

  • G. Savage, J. Csecs, G. Davies, H. Critchley, J. Eccles (2021). "#3085 Relationship between variant connective tissue (hypermobility) and autism sensory processing: externally oriented thinking as a mediator". J Neurol Neurosurg Psychiatry, 92(8). doi:10.1136/jnnp-2021-bnpa.19

  • H. Emma Clare Sharp, H. Critchley, J. Eccles (2021). "Connecting brain and body: Transdiagnostic relevance of connective tissue variants to neuropsychiatric symptom expression". WJP, 11(10). doi:10.5498/wjp.v11.i10.805

  • P. Singh, A. Agnihotri, M. Pathak, A. Shirazi, R. Tiwari, V. Sreenivas, R. Sagar, G. Makharia (2012). "Psychiatric, Somatic and Other Functional Gastrointestinal Disorders in Patients With Irritable Bowel Syndrome at a Tertiary Care Center". J Neurogastroenterol Motil, 18(3). doi:10.5056/jnm.2012.18.3.324

  • T. Smith, V. Easton, H. Bacon, E. Jerman, K. Armon, F. Poland, A. Macgregor (2014). "The relationship between benign joint hypermobility syndrome and psychological distress: a systematic review and meta-analysis". Rheumatology, 53(1). doi:10.1093/rheumatology/ket317

  • H. Tager‐Flusberg, C. Kasari (2013). "Minimally Verbal School‐Aged Children with Autism Spectrum Disorder: The Neglected End of the Spectrum". Autism Research, 6(6). doi:10.1002/aur.1329

  • R. Treede, W. Rief, A. Barke, Q. Aziz, M. Bennett, R. Benoliel, M. Cohen, S. Evers, N. Finnerup, M. First, M. Adele Giamberardino, S. Kaasa, B. Korwisi, E. Kosek, P. Lavand'homme, M. Nicholas, S. Perrot, J. Scholz, S. Schug, B. Smith, P. Svensson, J. W.S. Vlaeyen, S. Wang (2019). "Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)". Pain, 160(1). doi:10.1097/j.pain.0000000000001384

  • S. Vaughan, F. McGlone, H. Poole, D. Moore (2020). "A Quantitative Sensory Testing Approach to Pain in Autism Spectrum Disorders". J Autism Dev Disord, 50(5). doi:10.1007/s10803-019-03918-0

  • J. Voerman, C. de Klerk, K. Vander Heyden, J. Passchier, W. Idema, R. Timman, J. Jolles (2017). "Pain is Associated With Poorer Grades, Reduced Emotional Well-Being, and Attention Problems in Adolescents". The Clinical Journal of Pain, 33(1). doi:10.1097/ajp.0000000000000367

  • J. Vu, V. Kushnir, B. Cassell, C. Gyawali, G. Sayuk (2014). "The impact of psychiatric and extraintestinal comorbidity on quality of life and bowel symptom burden in functional GI disorders". Neurogastroenterology Motil, 26(9). doi:10.1111/nmo.12396

  • D. Whitney, D. Shapiro (2019). "National Prevalence of Pain Among Children and Adolescents With Autism Spectrum Disorders". JAMA Pediatr, 173(12). doi:10.1001/jamapediatrics.2019.3826

  • M. Wong, E. Widerstrom-Noga (2021). "Pain evaluation and management in neurodevelopmental conditions". Diagnosis, Management and Modeling of Neurodevelopmental Disorders. doi:10.1016/b978-0-12-817988-8.00033-6

  • S. Young, J. Hollingdale, M. Absoud, P. Bolton, P. Branney, W. Colley, E. Craze, M. Dave, Q. Deeley, E. Farrag, G. Gudjonsson, P. Hill, H. Liang, C. Murphy, P. Mackintosh, M. Murin, F. O’Regan, D. Ougrin, P. Rios, N. Stover, E. Taylor, E. Woodhouse (2020). "Guidance for identification and treatment of individuals with attention deficit/hyperactivity disorder and autism spectrum disorder based upon expert consensus". BMC Med, 18(1). doi:10.1186/s12916-020-01585-y


 
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